Onnit Alpha Brain OrganicNewsroom Review

Onnit’s Alpha Brain is a powerful blend of natural and semi-natural Nootropics. amino acids, and herbal compounds that have been proven in clinical trials to help boost overall cognitive performance. Nootropics are a class of supplements that are able to help boost brain performance and health in many numbers of ways.

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Clinical Support

Onnit’s Alpha Brain is one of few such Nootropics that have clinical data to back up their claims. Alpha Brain has been proven to promote alpha brain waves, enhance verbal skills, and overall cognitive processing speed. These results may very well vary from person to person, and you should always approach new supplements with caution.

Quick Facts

While this product may not be suited for everyone, understanding the different compounds and how they may work to benefit your brain function can help to make an informed decision. Here are some quick facts about Alpha Brain:

  • Available Sizes: 90, 60, 30
  • Serving Size: 2 Capsules
  • Inactive Ingredients: Vegetarian Caps, Rice Hull Concentrate, Dicalcium Phosphate
  • cGMP: Yes
  • Availability: Online and some retail stores

There’s more to qualifying a supplement than just these three facets. We believe formulation, flow agents, emulsifiers, and even availability all contribute to the value offered by supplements. Below you’ll find an outline of several ingredients found in Onnit’s Alpha Brain and a bit of discussion on why they’re important.

Alpha Brain banner
Alpha Brain by Onnit is a Popular ‘Designer’ Nootropic Containing Many Natural Herbal Compounds

Synergistic Nootropic Blend

Onnit’s Alpha Brain features a laundry list of powerful Nootropic Compounds that have been designed to help facilitate optimal brain function. Presumably, Onnit Alpha Brain was named for a naturally calm and focused state of our brains when alpha waves are the predominant brain activity. This particular frequency within our brain is also known to be associated with an increased amount of creativity and reduced depression. The study of the effects of alpha wave states within our brain has been studied with deep interest for many years and has many different facets to consider.


Vinpocetine is a Nootropic that is regarded officially as being a synthetic compound, though it is as close to being all-natural as a compound can get. This curious compound is extracted from the Periwinkle plant and has been around since the late 1970’s. Vinpocetine helps promote a higher amount of blood flow throughout the neural pathways of the brain. This offers general neuroprotective support and has been shown to benefit those suffering from stroke-related damage particularly. The benefits associated with increased blood flow to the brain is a no-brainer for any nootropic.


Pterostilbene is a potent compound that offers several benefits for both brain and bodily health as well. Pterostilbene is a powerful natural antioxidant found in high concentrations within blueberries. Antioxidants are useful in their ability to help reduce damage from oxidation throughout the body and can help stave off some of the age-related damages the body. For instance, one study found that dietary-achievable amounts of Pterostilbene were able to demonstrate remarkable cognitive enhancing effects that would also likely help address age-related mental issues such as Alzheimer’s disease. These findings also indicated that Pterostilbene was much more effective in such cases than that of Resveratrol.

L-Alpha Glycerylphosphorylcholine (Alpha GPC)

Alpha GPC is a form of Choline that is known to be very effective in its ability to cross the blood-brain barrier. This compound is revered within the Nootropics community as being one of the most-effective choline compounds. Research has shown that Alpha GPC demonstrates the ability to help upregulate the amount of acetylcholine within the brain—which is regarded as being responsible for those quick-synaptic firing experiences of making effective split-decisions.

Acetylcholine is largely ‘balanced out’ by Gamma-Aminobutyric acid (GABA) and represents one of the fundamental dynamics of our neural pathways—the balance of acetylcholine and gamma-aminobutyric acid. Alpha GPC is also one of the few supplements that have been shown to drastically increase human growth hormone naturally. Choline, in various forms, is commonly used alongside other nootropics to help balance things out.


L-Theanine is a natural compound that is found in many antioxidant-rich plants, most commonly recognized as being in green tea and matcha powder. L-Theanine has demonstrated the ability to calm the mind without contributing any drowsiness effect or causing physical tiredness. Fans of green tea will likely describe this effect as being a less jittery caffeine buzz, and L-Theanine is regarded by most Nootropics enthusiasts as an inseparable companion to caffeine.

Research has also shown that L-Theanine is effective in helping to address some symptoms of ADHD, as well as promoting more restful sleep. For this reason, L-Theanine is considered one of the go-to non-prescription sleep aids available on the consumer market. We’ve heard reports of this compound eliciting stimulatory effects also, so we suggest taking it in an isolated form to best gauge how it will affect you (especially if you have sleep issues!)


Phosphatidylserine is among the most-prevalent lipids found within the brain and accounts for 15% of all phospholipids found in neural cells. The brain is the fattiest organ in the entire human body and consists of mostly water and as much as 60% lipids (fat). As we age, we undergo an accumulation of oxidative stress from the many redox reactions that occur within our body. One of the places in which we see an accumulation of this stress’ fallout is in the neural lipid composition.

Phosphatidylserine is one of the few natural compounds able to make an FDA-qualified health claim for benefiting cognitive health

The impacts of this fallout are thought to be a large factor in the progression of many neurodegenerative diseases. For example, a person of 90 years may have as much as 40% fewer neural lipids as a healthy young person. This paints a daunting image of the relationship between fatty acids and brain health. Phosphatidylserine’s large presence in neural cells suggests that maintaining healthy levels may help reduce the likelihood of such diseases as Alzheimer’s. Phosphatidylserine is one of the few natural compounds able to make an FDA-qualified health claim for benefiting cognitive health (or anything, for that matter!)

Onnit Alpha Brain Review
Alpha Brain has clinical evidence to support its claim of optimizing cognitive performance

Remarkable Nutritional Company

Onnit is a remarkable mission-driven company that focuses on the power of nutrition and fitness to improve lives. They have rallied an impressive amount of support from performance athletes in recent years and continue to roll out impressive nutritional products. Onnit’s Alpha Brain is only one example of their dedication to better understanding the role nutritional balance plays in long-term health. To see a full list of the ingredients in Alpha Brain, check out the detailed product information page on the Onnit website.

History of Onnit

Onnit was founded in 2010 by CEO Aubrey Marcus and has since experienced a commendable rise to success through avid customer support and endorsements by notable personalities such as Joe Rogan. Well-known for his famous podcast The Joe Rogan Experience, Rogan feels that Alpha Brain “seems to fire up your brain at a higher RPM level“. Through these many notable partnerships and event sponsorship, Onnit has risen quickly to the top of a budding consumer market that can best be described as Self Optimization. This is a bit of a pseudo-term, but it basically means working to create a better version of yourself mentally, physically, and even emotionally.

Where to Buy

Alpha Brain products are available directly from Onnit as well as other online retailers like Amazon, and also in some stores such as the Vitamin Shoppe and Whole Foods. Online pricing is likely to be lower and if you can catch Alpha Brain during one of Onnit’s famous flash sales you can save tremendously! Onnit offers special pricing for many first-time orders, and if you decide Alpha Brain is something you’d like to have for regular use—they offer subscription-based discounts that can save an additional 15%. You can view the latest prices and availability on the official Alpha Brain page.

Final Thoughts

Self-optimization is just another word for something that many of us have been doing day in and day out—trying to feel better. Alpha Brain is designed to help take some of the guesswork out of creating a well-balanced nootropic stack for those seeking a more optimized cognitive performance. This supplement contains many compounds well-regarded as effective nootropics and has some clinical data specific to it to support its claims. All things considered: if you’re looking for a designer Nootropic this is one of the better choices on the market—though we believe its a bit overpriced.

Onnit Alpha Brain OrganicNewsroom Review
Alpha Brain by Onnit
Alpha Brain is a natural nootropic blend with clinical support for offering cognitive enhancement in learning and memory-based tasks. This supplement contains notable nootropics compounds such as Alpha-GPC, Phosphatidylserine, and vinpocetine. We think it's a well-designed supplement but comes in a little overpriced.
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