Onnit’s Alpha Brain is a powerful blend of natural and semi-natural Nootropics. amino acids, and herbal compounds that has been proven in clinical trials to help boost overall cognitive performance. Nootropics are a class of supplements that  are able to help boost brain performance and health in many numbers of ways. This Alpha Brain review is meant to help you better understand the individual compounds found in this synergistic product by Onnit, and help you decide if it may be something for you.

Limitless Potential

The Onnit Alpha Brain supplement is one of few such Nootropics that have clinical data to back up their claims 1. Alpha Brain has been proven to promote alpha brain waves, enhance verbal skills, and overall cognitive processing speed. These results may very well vary from person to person, and you should always approach new supplements with caution.  While this product may not be suited for everyone, understanding the different compounds and how they may work to benefit your brain function can help to make an informed decision.

Synergistic Nootropic Blend

Onnit’s Alpha Brain features a laundry list of powerful Nootropic Compounds that has been designed to help facilitate optimal brain function. Presumably, Onnit Alpha Brain was named for a natural state that our brains functions in where Alpha Waves are the predominant brain activity 2. This particular frequency within our brain is known be associated with an increased amount of creativity and reduced depression 3. The study of the effects of alpha wave states within our brain has been studied with deep interest for many years, and has many different facets to consider. Science still ultimately has little clue as to how the brain works—continued research into the frontiers of our understanding continue to paint such compounds as Nootropics as being potentially beneficial. To better understand the role that Alpha Brain can play to enhance your cognitive function, let’s take a look at some of the principle ingredients.


Vinpocetine is a Nootropic that is regarded officially as being a synthetic compound, though it is as close to being all-natural as a compound can get. This curious compound is extracted from the Periwinkle plant, and has been around since the late 1970’s. Generally speaking, Vinpocetine helps promote a higher amount of blood flow throughout the neural pathways of the brain, and is also known to help provide neuro-protective support as well. The inclusion of Vinpocetine in the Alpha Brain product is likely multi-purpose—as increased blood flow would alone increase brain performance, but would likely also help to deliver other compounds of the blend more effectively.


Pterostilbene is a potent compound that offers several benefits for both brain and bodily health as well. Pterostilbene is a powerful natural antioxidant found in high concentrations within blueberries. Antioxidants are useful in their ability to help reduce damage from oxidation throughout the body, and can help stave off some of the age-related damages the body. For instance, one study found that dietary-achievable amounts of Pterostilbene was able to demonstrate remarkable cognitive enhancing effects that would also likely help address age-related mental issues such as Alzheimer’s 4. These findings also indicated that Pterostilbene was much more effective in such cases than that of Resveratrol.

L-Alpha Glycerylphosphorylcholine (Alpha GPC)

Alpha GPC is a form of Choline that is known to be very effective in it’s ability to cross the blood brain barrier. This compound is revered within the Nootropics community as being one of the most-effective choline compounds. Research has shown that Alpha GPC demonstrates the ability to help upregulate the amount of acetylcholine within the brain—which is regarded as being responsible for those quick-synaptic firing experiences of making effective split-decisions 5. Acetylcholine is largely ‘balanced out’ by Gamma Aminobutyric acid (GABA) which both comprise the majority of neurotransmitters found within the human brain. Alpha GPC is also one of the few supplements that have been shown to drastically increase human growth hormone naturally. Choline has anecdotally been related to helping to effectively counteract headache like symptoms during and after intense mental focus.


L-Theanine is a natural compound that is found in many antioxidant-rich plants, most commonly recognized as being in green tea and matcha powder. L-Theanine has demonstrated the ability to calm the mind without contributing any drowsiness effect or causing physical tiredness. Fans of green tea will likely describe this effect as being a less jittery caffeine buzz, and L-Theanine is regarded by most Nootropics enthusiasts as an inseparable companion to caffeine. Research has also shown that L-Theanine is effective in helping to address some symptoms of ADHD, as well as promoting more restful sleep 6 Anecdotal evidence describes this natural compound as being able to provide a bit of a stimulating mental effect on it’s own, though more from the perspective of simply wanting to think more since one becomes more clearly focused.


Phosphatidylserine is among the most-prevalent lipids found within the brain, and accounts for 15% of all phospholipids found in neural cells 7. The brain is the fattiest organ in the entire human body, and consists of mostly water and as much as 60% lipids (fat) 8. As we age, we undergo an accumulation of oxidative stress from the many redox reactions that occur within our body. One of the places in which we see an accumulation of this stress’ fallout is in the neural lipid composition. A person of 90 years may have as much as 40% less neural lipids as a healthy young person 9. This paints a tremendous picture of the relationship between fatty-acids and brain health. Considering that Phosphatidylserine accounts for such a large amount of the brain’s phospholipids, it stands to reason that this compound could be very powerful in helping to promote long-term brain health and acute cognitive function.

Onnit Alpha Brain Review

Remarkable Nutritional Company

Onnit is a remarkable mission driven company that focuses on the powerful of nutrition and fitness to improve lives. Onnit Alpha Brain is one example of their dedication to better understanding the resonance and synergy between many natural compounds such as the one’s listed above. To see a full list of the ingredients in Alpha Brain, check out the detailed product information page on the Onnit website. Many manufacturers only half-heartedly attempt to describe their products, but Onnit has dedicated themselves to providing their customers with truly insightful descriptions, and access to the clinical data they’ve used to help design their products.

Onnit was founded in 2010 by CEO Aubrey Marcus and has since experienced a commendable rise to success through avid customer support and endorsements by notable personalities such as Joe Rogan. Well-known for his famous podcast The Joe Rogan Experience, Rogan feels that Alpha Brain “seems to fire up your brain at a higher RPM level“. Through these many notable partnerships and event sponsorship, Onnit has risen quickly to the top of a budding consumer market that can best be described as Self Optimization. This is a bit of a pseudo-term, but it basically means working to create a better version of yourself mentally, physically, and even emotionally.

Where to Buy

Alpha Brain products sold primarily through Onnit’s website, and through select online retailer like Amazon. Recent partnerships with retailers such as Whole Foods, Sprouts, and The Vitamin Shoppe have allowed Alpha Brain and a handful of their other nutrition products to be available in local stores. As with all supplements, you’ll find the better deal online—and buying directly from the manufacturer is the best way to ensure product purity and potency. Onnit offers special pricing for many first-time orders, and if you decide Alpha Brain is something you’d like to have for regular use—they offer subscription-based discounts that can save an additional 15%. You can view the latest prices and availability on the official Alpha Brain page.

Final Thoughts

Self-optimization is just another word for something that many of us have been doing day in and day out—working to forge a stronger version of our self. Modern health is in a state of crisis, and alternatives to pharmaceuticals have never been more popular. It’s important that you take heed of which supplement brands you trust your health to, and realize that many companies are simply out to make money with little regard for your long-term health. Onnit is among the most respected nutrition brands on the market, and their dedication to furthering the endeavor of self optimization has become a near-legendary expression of passion.

Onnit Alpha Brain Review
Onnit Alpha Brain
Onnit Alpha Brain is a potent designer Nootropics supplement with clinical data to back it's efficacy. This supplement is packed with powerful natural compounds meant to fuel your brain and help sustain peak performance during times of extreme focus.
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